Mitochondrial replacement therapy requires oocytes of women whose mitochondrial DNA will be transmitted to resultant children. These techniques are scientifically, ethically and socially controversial; it is likely that some women who donate their oocytes for general in vitro fertilisation usage would nevertheless oppose their genetic material being used in MRT. The possibility of oocytes being used in MRT is therefore relevant to oocyte donation and should be included in the consent process when applicable. In present circumstances, specific consent should be (...) obtained. However, once MRT becomes more routine, such consent could be incorporated into the general consent process for oocyte donation. The reported lack of proper consent for MRT from the oocyte donor in the first baby born via the technique is an ethical failing and should be corrected in any future practice of MRT. (shrink)

ABSTRACTThis article, which summarises some of the main arguments of Analogical Investigations [Lloyd 2015], undertakes a comparative cross-cultural critique of the dominant Western view that downgrades analogy especially when that is contrasted unfavourably with a notion of axiomatic-deductive demonstration aiming to secure incontrovertible conclusions. It draws on materials from ancient Greece, ancient China and modern social anthropology and philosophy of science to explore the problems of translation and mutual intelligibility. It develops the idea of semantic stretch to qualify the literal/metaphorical (...) dichotomy and the notion of the multidimensionality of reality to clarify aspects of the controversy between realism and relativism. (shrink)

Given the sordid history of injustices linking genetics to race and ethnicity, considerations of justice are central to ensuring the responsible development of precision medicine programmes around the world. While considerations of justice may be in tension with other areas of concern, such as scientific value or privacy, there are also tensions between different aspects of justice. This paper focuses on three particular aspects of justice relevant to this precision medicine: social justice, distributive justice and human rights. We describe the (...) implications of each for the use of race and ethnicity in precision medicine, and also how they intersect and potentially conflict with each another. By attending to these intersections, we aim to enrich and add nuance to debates over how best to proceed with precision medicine initiatives. (shrink)

It is a landmark theorem of McKinsey and Tarski that if we interpret modal diamond as closure, then \ is the logic of any dense-in-itself metrizable space. The McKinsey–Tarski Theorem relies heavily on a metric that gives rise to the topology. We give a new and more topological proof of the theorem, utilizing Bing’s Metrization Theorem.

A significant proportion of conservationists' work is directed towards efforts to save disappearing species. This relies upon the belief that species extinction is undesirable. When justifications are offered for this belief, they very often rest upon the assumption that extinction brought about by humans is different in kind from other forms of extinction. This paper examines this assumption and reveals that there is indeed good reason to suppose current anthropogenic extinctions to be different in kind from extinctions brought about at (...) other times or by other factors. Having considered – and rejected – quantity and rate of extinction as useful distinguishing factors, four alternative arguments are offered, each identifying a way in which anthropogenic extinction is significantly different from other forms of extinction, even mass extinction: (1) Humans are a different kind of natural cause from other causes of extinction; (2) Extinctions brought about by humans are uniquely persistent; (3) Anthropogenic extinctions are effectively random whereas past mass extinctions are rule-bound; (4) The impact of the current anthropogenic extinction event differs from the impact of other extinction events of the past, such that future recovery may not follow past patterns. Together, these four arguments suggest that the present-day extinction event brought about by humans may be unprecedented and that we cannot clearly extrapolate from past to present recovery from extinctions. Although insufficient as justification for the claim that present-day extinctions are undesirable, the arguments provide some ammunition for conservationists' conviction that species extinction – in which humans play an accelerating role – ought to be prevented. (shrink)

Individual health assessments (IHAs) for asymptomatic individuals provide a challenge to traditional distinctions between patient care and non-medical practice. They may involve undue radiation exposure, lead to false positives, and involve high out-of-pocket costs for recipients. A recent paper (Journal of the American College of Radiology 13(12): 1447–1457.e1, 2016) has criticised the use of IHAs and argued that recipients should be classified as ‘presenters’, not ‘patients’, to distinguish it from regular medical care. I critique this classificatory move, on two grounds: (...) one, it is conceptually suspect. Two, it obviates the medical ethics framework for IHAs, potentially exposing recipients of IHAs to lower standards of oversight and protection. Responsible regulation of IHAs will be easier to ethically justify if those seeking IHAs are considered patients and not merely presenters. (shrink)

The aim of this article is to offer what I consider to be necessary substantiati for the view that the description of the walk which acts as a frame for the singing contest in Id. 7 is based on a precise knowledge of the geography of t island of Cos and that the poem thus displays a topographical realism unique Greek pastoral.

Hastings Center Report, Volume 52, Issue 3, Page 31-33, May–June 2022.

¡Cuán lejos estamos del clasicismo, y cuánto necesitamos de él! La necesidad de incorporar más estudios humanísticos es una necesidad que no puede sino sonar hoy terriblemente arcaica, inadaptada a los tiempos que –literalmente– corren, inútil a una democracia que ha perdido el rumbo y que trepida a la consolidación de lo técnico, donde la deliberación ha sido reemplazada por lo instintivo, por la irreflexión, por el espectáculo; en fin, si hay una consigna que hoy suena como una bella sinfonía (...) opacada por el ruido circundante, no es sino aquella que clama por la reivindicación del humanismo en nuestra educación como una condición ineludible de una democracia realmente deliberativa. Esto ya lo había atisbado nuestra poetisa, cuando señaló que las briznas apenas asomadas del humanismo fueron quemadas en varios países “y que lo científico entró con una presencia borrosa de fantasma, es decir, sin capacidad para suceder a la patrona arrojada de las aulas” (98). (shrink)

In the history of Russian philosophy, V. S. Solovyov is known as one of the prominent spokesmen of theological idealism. Lenin more than once pointed to the need to combat the ideas of this philosopher . He quite properly regarded them as the theoretical foundation of the ideology of "liberal renegacy.".

This volume presents new texts of Cicero's dialogues on political philosophy, De Re Publica and De Legibus, together with corrected versions of the editor's previously published editions of Cato Maior de Senectute and Laelius de Amicitia. The texts are based on a full reconsideration of the manuscript evidence and are presented in a clear and readable form.